CHEMOTHERAPY REGIMEN ACRONYMS , COMPONENTS AND INDICATIONS

ACRONYM

COMPONENTS

INDICATION

7+3, also known as DA or DAC 

7 days of Ara-C (cytarabine) plus 3 days of an anthracycline antibiotic, either daunorubicin (DA or DAC variant) 

Acute myelogenous leukemia, excluding acute promyelocytic leukemia

ABVD

doxorubicin (Adriamycin), bleomycin, vinblastine, dacarbazine

Hodgkin's lymphoma

AC

doxorubicin (Adriamycin), cyclophosphamide

breast cancer

BACOD

bleomycin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), dexamethasone

Non-Hodgkin lymphomas

BEACOPP

bleomycin, etoposide, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), procarbazine, prednisone

Hodgkin's lymphoma

BEP

bleomycin, etoposide, platinum agent

testicular cancer, germ cell tumors

CA

cyclophosphamide, doxorubicin (Adriamycin) (same as AC)

breast cancer

CAF

cyclophosphamide, doxorubicin (Adriamycin), fluorouracil (5-FU)

breast cancer

CAPOX or XELOX

capecitabine and oxaliplatin

colorectal cancer

CAV

cyclophosphamide, doxorubicin (Adriamycin), vincristine

lung cancer

CBV

cyclophosphamide, BCNU (carmustine), VP-16 (etoposide)

lymphoma

CHOEP

cyclophosphamide, hydroxydaunorubicin (doxorubicin), etoposide, vincristine (Oncovin), prednisone

Non-Hodgkin lymphomas

CEPP

cyclophosphamide, etoposide, procarbazine, prednisone

Non-Hodgkin Lymphomas

ChlVPP/EVA

chlorambucil, vincristine (Oncovin), procarbazine, prednisone, etoposide, vinblastine, doxorubicin (Adriamycin)

Hodgkin's lymphoma

CHOP

cyclophosphamide, hydroxydaunorubicin (doxorubicin), vincristine (Oncovin), prednisone

non-Hodgkin lymphoma

CHOP-R or R-CHOP

CHOP + rituximab

B cell non-Hodgkin lymphoma

ClaPD

clarithromycin, pomalidomide, dexamethasone

multiple myeloma

CMF

cyclophosphamide, methotrexate, fluorouracil (5-FU)

breast cancer

CMV

cisplatin, methotrexate, vinblastine

transitional bladder carcinoma

COP or CVP

cyclophosphamide, Oncovin (vincristine), prednisone

non-Hodgkin lymphoma in patients with history of cardiovascular disease

COPP

cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone

Hodgkin's lymphoma

CT or TC

docetaxel (Taxotere), cyclophosphamide

breast cancer

CTD

cyclophosphamide, thalidomide, dexamethasone

AL amyloidosis

CVAD and Hyper-CVAD

cyclophosphamide, vincristine, doxorubicin (Adriamycin), dexamethasone

aggressive non-Hodgkin lymphoma, lymphoblastic lymphoma, some forms of leukemia

CVE

carboplatin, vincristine, etoposide

retinoblastoma

CYBORD

cyclophosphamide, bortezomib, dexamethasone

multiple myeloma, AL amyloidosis

DA or DAC

daunorubicin x 3 days plus ara-C (cytarabine) x 7 days, a variant of 7+3 regimen

Acute myeloid leukemia, excluding acute promyelocytic leukemia

DAT

daunorubicin, cytarabine (ara-C), tioguanine

Acute myeloid leukemia

DCEP

dexamethasone, cyclophosphamide, etoposide, platinum agent

relapsed or refractory multiple myeloma

DHAP

dexamethasone (a steroid hormone), cytarabine (ara-C), platinum agent

Non-Hodgkin lymphomas

DHAP-R or R-DHAP

dexamethasone (a steroid hormone), cytarabine (ara-C), platinum agent plus rituximab

Non-Hodgkin lymphomas

DICE

dexamethasone, ifosfamide, cisplatin, etoposide (VP-16)

aggressive relapsed lymphomas, progressive neuroblastoma

DT-PACE

dexamethasone, thalidomide, platinum agent, doxorubicin (Adriamycin), cyclophosphamide, etoposide

multiple myeloma

EC

epirubicin, cyclophosphamide

breast cancer

ECF (MAGIC)

epirubicin, cisplatin, fluorouracil (5-FU)

gastric cancer and cancer of the esophagogastric junction (Siewert classification III)

EOX

epirubicin, oxaliplatin, capecitabine

esophageal Cancer, gastric Cancer

EP

etoposide, platinum agent

testicular cancer, germ cell tumors

EPOCH

etoposide, prednisone, vincristine (Oncovin), cyclophosphamide, and hydroxydaunorubicin

Non-Hodgkin lymphomas

EPOCH-R or R-EPOCH

etoposide, prednisone, vincristine (Oncovin), cyclophosphamide, and hydroxydaunorubicin plus rituximab

B cell Non-Hodgkin lymphomas

ESHAP

etoposide, methylprednisolone (a steroid hormone), cytarabine (ara-C), platinum agent

Non-Hodgkin lymphoma

ESHAP-R or R-ESHAP

etoposide, methylprednisolone (a steroid hormone), cytarabine (ara-C), platinum agent plus rituximab

Non-Hodgkin lymphoma

FAM

fluorouracil, doxorubicin (Adriamycin), mitomycin

gastric cancer

FAMTX

fluorouracil, doxorubicin (Adriamycin), methotrexate

gastric cancer

FCM or FMC

fludarabine, cyclophosphamide, mitoxantrone

B cell non-Hodgkin lymphoma

FCM-R or R-FCM or R-FMC or FMC-R

fludarabine, cyclophosphamide, mitoxantrone plus rituximab

B cell non-Hodgkin lymphoma

FCR

fludarabine, cyclophosphamide, rituximab

B cell non-Hodgkin lymphoma

FM

fludarabine, mitoxantrone

B cell non-Hodgkin lymphoma

FM-R or R-FM or RFM or FMR

fludarabine, mitoxantrone, and rituximab

B cell non-Hodgkin lymphoma

FEC

fluorouracil (5-FU), epirubicin, cyclophosphamide

breast cancer

FEC-T

fluorouracil (5-FU), epirubicin, cyclophosphamide together, followed by docetaxel (Taxotere)

breast cancer

FL (also known as Mayo)

fluorouracil (5-FU), leucovorin (folinic acid)

colorectal cancer

FLAG

fludarabine, cytarabine, G-CSF

relapsed or refractory acute myelogenous leukemia

FLAG-Ida or FLAG-IDA or IDA-FLAG or Ida-FLAG

fludarabine, cytarabine, idarubicin, G-CSF

relapsed or refractory acute myelogenous leukemia

FLAG-Mito or FLAG-MITO or Mito-FLAG or MITO-FLAG or FLANG[citation needed]

mitoxantrone, fludarabine, cytarabine, G-CSF

relapsed or refractory acute myelogenous leukemia

FLAMSA

fludarabine, cytarabine, amsacrine

myelodysplastic syndrome, acute myeloid leukemia

FLAMSA-BU or FLAMSA-Bu

fludarabine, cytarabine, amsacrine, busulfan

myelodysplastic syndrome, acute myeloid leukemia

FLAMSA-MEL or FLAMSA-Mel

fludarabine, cytarabine, amsacrine, melphalan

myelodysplastic syndrome, acute myeloid leukemia

FLOT

fluorouracil (5-FU), leucovorin (folinic acid), oxaliplatin, docetaxel

esophageal cancer, gastric cancer

FOLFIRI

fluorouracil (5-FU), leucovorin (folinic acid), irinotecan

colorectal cancer

FOLFIRINOX

fluorouracil (5-FU), leucovorin (folinic acid), irinotecan, oxaliplatin

pancreatic cancer

FOLFOX

fluorouracil (5-FU), leucovorin (folinic acid), oxaliplatin

colorectal cancer

GC

gemcitabine, cisplatin gemcitabine, dexamethasone, and cisplatin

 

GDP

gemcitabine, dexamethasone, cisplatin

Non-Hodgkin lymphomas and Hodgkin lymphoma

GemOx or GEMOX

gemcitabine, oxaliplatin

Non-Hodgkin lymphomas

GVD

gemcitabine, vinorelbine, pegylated liposomal doxorubicin

Hodgkin lymphoma

GemOx-R or GEMOX-R or R-GemOx or R-GEMOX

gemcitabine, oxaliplatin, rituximab

Non-Hodgkin lymphomas

IA or IAC

idarubicin x 3 days plus Ara-C (cytarabine) x 7 days, a variant of classical 7+3 regimen

Acute myelogenous leukemia, excluding acute promyelocytic leukemia

ICE

ifosfamide, carboplatin, etoposide (VP-16)

aggressive lymphomas, progressive neuroblastoma

ICE-R or R-ICE or RICE

ICE + rituximab

high-risk progressive or recurrent lymphomas

IFL

irinotecan, leucovorin (folinic acid), fluorouracil

colorectal cancer

IVA

ifosfamide, vincristine, actinomycin D

rhabdomyosarcoma

MAP or MAPIE

Doxorubicin (Adriamycin), Cisplatin, Methotrexate, Ifosfamide (Ifex), Etoposide (Vepesid)

Bone cancer, Osteosarcoma

m-BACOD

methotrexate, bleomycin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), dexamethasone

non-Hodgkin lymphoma

MACOP-B

methotrexate, leucovorin (folinic acid), doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), prednisone, bleomycin

non-Hodgkin lymphoma

MAID

mesna, doxorubicin, ifosfamide, dacarbazine

soft-tissue sarcoma

MINE

mesna, ifosfamide, novantrone, etoposide

Non-Hodgkin lymphomas and Hodgkin lymphoma in relapse or refractory cases

MINE-R or R-MINE

mesna, ifosfamide, novantrone, etoposide plus rituximab

Non-Hodgkin lymphomas and Hodgkin lymphoma in relapse or refractory cases

MMM

mitomycin, methotrexate, mitoxantrone

breast cancer

MOPP

mechlorethamine, vincristine (Oncovin), procarbazine, prednisone

Hodgkin's lymphoma

MVAC

methotrexate, vinblastine, doxorubicin (Adriamycin), cisplatin

advanced bladder cancer[4]

MVP

mitomycin, vindesine, cisplatin

lung cancer and mesothelioma

NP

cisplatin, vinorelbine

non-small cell lung carcinoma

PACE

platinum agent, doxorubicin (Adriamycin), cyclophosphamide, etoposide

 

PCV

Procarbazine, CCNU (lomustine), vincristine

brain tumors

PEB

cisplatin, etoposide, bleomycin

non-seminomatous germ cell tumors

PEI

cisplatin, etoposide, ifosfamide

small-cell lung carcinoma

platin + taxane[5]

cisplatin/carboplatin, paclitaxel/docetaxel

ovarian cancer

POMP

6-mercaptopurine (Purinethol), vincristine (Oncovin), methotrexate, and prednisone

acute adult leukemia[6]

ProMACE-MOPP

methotrexate, doxorubicin (Adriamycin), cyclophosphamide, etoposide + MOPP

non-Hodgkin lymphoma

ProMACE-CytaBOM

prednisone, doxorubicin (Adriamycin), cyclophosphamide, etoposide, cytarabine, bleomycin, vincristine (Oncovin), methotrexate, leucovorin

non-Hodgkin lymphoma

RdC

lenalidomide (Revlimid), dexamethasone, cyclophosphamide

AL amyloidosis

R-Benda

rituximab + bendamustine

follicular lymphoma and MALT lymphoma[7]

R-DHAP or DHAP-R

rituximab + DHAP; that is, rituximab, dexamethasone (a steroid hormone), cytarabine (ara-C), platinum agent

relapsed non-Hodgkin's lymphoma and Hodgkin's lymphoma

R-FCM or FCM-R

rituximab + FCM; that is, rituximab, fludarabine, cyclophosphamide, mitoxantrone

B cell non-Hodgkin lymphoma

R-ICE or ICE-R or RICE

rituximab + ICE; that is, rituximab, ifosfamide, carboplatin, etoposide

high-risk progressive or recurrent lymphomas

RVD

lenalidomide (Revlimid), bortezomib, dexamethasone

 

Stanford V

doxorubicin (Adriamycin), mechlorethamine, bleomycin, vinblastine, vincristine, etoposide, prednisone

Hodgkin lymphoma

TAC or ACT

docetaxel (Taxotere) or paclitaxel (Taxol), doxorubicin (Adriamycin), cyclophosphamide

breast cancer ("TAC" can also refer to tetracaine-adrenaline-cocaine, used as local anesthetic)

TAD

tioguanine, cytarabine (ara-C), daunorubicin

acute myeloid leukemia

TC or CT

docetaxel (Taxotere), cyclophosphamide

breast cancer

TCH

docetaxel (Taxotere), carboplatin, trastuzumab (Herceptin)

breast cancer with positive HER2/neu receptor

TCHP

docetaxel (Taxotere), carboplatin, trastuzumab (Herceptin), pertuzumab (Perjeta)

breast cancer with positive HER2/neu receptor

Thal/Dex

thalidomide, dexamethasone

multiple myeloma

TIP

paclitaxel (Taxol), ifosfamide, platinum agent cisplatin (Platinol)

testicular cancer, germ cell tumors in salvage therapy

EE-4A

vincristine, actinomycin[8]

Wilms' tumor[8]

DD-4A

vincristine, actinomycin, doxorubicin (Adriamycin)[8]

Wilms' tumor[8]

VABCD

vinblastine, doxorubicin (Adriamycin), bleomycin, lomustine (CeeNU), dacarbazine

MOPP refractory Hodgkin's Lymphoma

VAC

vincristine, actinomycin, cyclophosphamide

rhabdomyosarcoma

VAD

vincristine, doxorubicin (Adriamycin), dexamethasone

multiple myeloma

VAMP

one of 3 combinations of vincristine and others

Hodgkin's lymphoma, leukemia, multiple myeloma

Regimen I

vincristine, doxorubicin (Adriamycin), etoposide, cyclophosphamide

Wilms' tumor[8]

VAPEC-B

vincristine, doxorubicin (Adriamycin), prednisone, etoposide, cyclophosphamide, bleomycin

Hodgkin's lymphoma

VD-PACE

bortezomib, dexamethasone plus platinum agent, doxorubicin (Adriamycin), cyclophosphamide, etoposide

multiple myeloma

VIFUP

vinorelbine, cisplatin, fluorouracil

locally advanced/metastatic breast cancer

VIP

vinblastine, ifosfamide, platinum agent, (etoposide (VP-16) may substitute for vinblastine, making a regimen sometimes referred to as VIP-16)[9][10]

testicular cancer, germ cell tumors

VTD-PACE

bortezomib (Velcade), thalidomide, dexamethasone plus platinum agent, doxorubicin (Adriamycin), cyclophosphamide, etoposide

multiple myeloma



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